Book your stay on our website
and save up to 10%
compared to Booking.com!
Check rooms and rates
From103US$ /night
Check-in
11Jan2026Select date
Check-out
12Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

9300 S Main Street, Houston, Texas, United States
-
Close to the Museum District
Great
8.9
9.3
/10
4.2
4.3
/5

Guest Room Features

Rooms include one king bed or two queen beds with bedside outlets, a plush duvet, and pillow selection options. Each room contains a 43-inch LCD HD TV, work desk with ergonomic chair, microwave, and mini refrigerator. High-speed wired and wireless internet access is provided throughout.

Complimentary Breakfast Service

A free Express Start Breakfast is served daily from 6:00 AM, featuring hot breakfast items. Coffee and tea are available in the lobby throughout the day.

Recreation & Fitness

The seasonal outdoor pool operates from 10:00 AM to 10:00 PM. The fitness center includes ellipticals, treadmills, stationary bikes, free weights, resistance bands, and water station. All cardio equipment has flat screens and headphones.

Medical Center Location

Located 9 km from Ensemble/HCC and 25 km from William P. Hobby Airport. The hotel provides free shuttle service to Texas Medical Center. NRG Stadium and Arena are 1 mile away, making it convenient for Texans football games, concerts, and the Houston Livestock Show and Rodeo.

Business & Meeting Facilities

A 24-hour business center offers printing, copying, and scanning services. Meeting spaces include a dividable room accommodating up to 66 people and a conference room for 33 people. Equipment includes LCD projectors, flip charts, and teleconferencing capabilities.

“The Holiday Inn Express & Suites near the Medical Center struck me as particularly well-suited for longer stays, with its in-room workspaces and included breakfast; plus, the location balances proximity to medical facilities with access to Houston's cultural side. I appreciate that it's set up to handle both families and business travelers, without feeling sterile. This hotel seems to have a solid grasp on practical comforts.”
Hotel logo
Grace WhitmanContent & Editorial Director at Familyhotels
View all

Choose from a variety of room types

Choose from a wide variety of rooms designed for families, including double rooms, family suites, and rooms with breakfast included
Specialty Room
2 persons
Air conditioning
Suite Mobility Access Roll Shower or Non-Smoking
2 persons
1 King-size bed
Shower
Air conditioning
Suite Only Hearing Accessible
2 persons
2 King Size Beds
Air conditioning
King Suite Communication Accessible
2 persons
1 King-size bed and 1 Sofa bed
Air conditioning
Click button to see more rooms
Show all rooms
Show all roomsLess

Availability and pricing for your selected dates

Book your family’s getaway in a snap with up-to-date availability and pricing!

Facilities

Each family-friendly hotel provides top-notch amenities for an unforgettable stay with your loved ones

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Outdoor swimming pool

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
Show more

Location

9300 S Main Street, Houston, Texas, United States
Map view
9300 S Main Street, Houston, Texas, United States
Nearby
1000 Block South Loop
World Birding Center
560 m
Restaurants
Hank's Ice Cream Parlor
30 m
9291 Main St
Popeyes Louisiana Kitchen
1.8 km
9120 Main St
Sleepys Po-Boys
1.6 km
9591 Main St
Five Guys
1.5 km
8505 S. Main Street Unit 380
Panda Express
1.5 km
8505 Main St
Denny's
2.4 km
3332 S Loop W
Sonic Drive-In
1.8 km
8504 Main Street
Explore Houston
Experience Houston
Top Attractions
Activities
Dining
Entertainment
NRG Stadium
17 minutes' walk
Home of the Houston Texans; a must-see for sports fans with tours available on non-game days.
Houston Zoo
50 minutes' walk
A premier zoological park hosting over 6,000 animals; great for families. Check for discount days.
Children's Museum of Houston
60 minutes' walk
Interactive exhibits designed for kids, encouraging creativity and learning; perfect for families.
Holocaust Museum Houston
35 minutes' walk
A moving tribute to Holocaust victims and survivors, showcasing educational exhibits and memorials.
Hermann Park
25 minutes' walk
A sprawling green space ideal for picnics, jogging, or relaxing under the trees; perfect for unwinding.
World Birding Center
10 minutes' walk
Nature reserve featuring birdwatching trails. A tranquil spot for wildlife enthusiasts and photographers.
Hank's Ice Cream Parlor
1 minute' walk
A local favorite known for its homemade ice cream. Perfect for a sweet treat after a long day.
Popeyes Louisiana Kitchen
25 minutes' walk
Famous for its spicy chicken and biscuits, offering a casual dining experience with quick service.
Sleepys Po-Boys
20 minutes' walk
New Orleans-style po-boys served in a cozy setting, boasting delicious sandwiches and local flavors.
Jazz Education
10 minutes' walk
A vibrant venue for live jazz music, hosting events that celebrate local talent and culture.
Six Flags Astroworld
20 minutes' drive
Amusement park featuring thrilling rides and family-friendly attractions. Great for adventure seekers.
Tips on navigating the city
City Centre
Houston15 min  ·  9.6 km
Airports
William P. Hobby Airport (HOU)33 min  ·  22.0 km
George Bush Intercontinental Airport - Houston (IAH)64 min  ·  42.1 km
Train
Reliant Park Station23 min  ·  1.9 km
Get access to exclusive early booking discounts for your family’s upcoming getaway
Book now and enjoy exclusive rates on your family vacation!
Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
The hotel Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg serves a full breakfast for free. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of floors:
4
Number of rooms:
47
Former name
holiday inn express & suites houston s - medical ctr area, an ihg hotel
FAQs
About Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg
What time is check-in and check-out at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Check-in is from 15:00 and check-out is by 12:00.
How far is Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg from William P. Hobby Airport?
The hotel is 15 km from William P. Hobby Airport.
What amenities are available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel features free Wi-Fi, an outdoor swimming pool, a fitness center, and a business center.
Is parking available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Complimentary self-parking is available for guests on-site.
What nearby attractions can guests visit from Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Nearby attractions include NRG Stadium (1 km) and the Museum District (6 km).
What dining options are available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel serves a complimentary hot breakfast daily; nearby dining options include Mama's Oven (0.5 km) and Pappas Bar-B-Q (1 km).
What room amenities can guests expect at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Rooms include a flat-screen TV, a coffee maker, a microwave, a refrigerator, and free toiletries.
Is there a fitness center at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Yes, there is a fitness center available for guests.
What safety measures are in place at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel has safety measures including a security presence to ensure guest safety.

Next best alternative

Consider them for your next trip.
Check-in
11Jan2026Select date
Check-out
12Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Need more options?
Check Top hotels near Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg
Staybridge Suites - Houston - Medical Center By Ihg Exterior photo
Mobile-only price

Staybridge Suites - Houston - Medical Center By Ihg

8.7
Great213 reviews
544m from property
USD 132USD 118
per night
The Reside Fully Furnished Condos - Medical Stays Welcome Houston Exterior photo
Mobile-only price

The Reside Fully Furnished Condos - Medical Stays Welcome Houston

8.8
Great250 reviews
888m from property
USD 130USD 117
per night
Hotel Ylem Houston Exterior photo
Mobile-only price

Hotel Ylem Houston

8.2
Great1544 reviews
1222m from property
USD 74USD 66
per night