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From397US$ /night
Check-in
26Feb2026Select date
Check-out
27Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

9300 S Main Street, Houston, Texas, United States
-
Close to the Museum District
Great
8.9
9.3
/10
4.2
4.2
/5

Guest Room Features

Rooms include one king bed or two queen beds with bedside outlets, a plush duvet, and pillow selection options. Each room contains a 43-inch LCD HD TV, work desk with ergonomic chair, microwave, and mini refrigerator. High-speed wired and wireless internet access is provided throughout.

Complimentary Breakfast Service

A free Express Start Breakfast is served daily from 6:00 AM, featuring hot breakfast items. Coffee and tea are available in the lobby throughout the day.

Recreation & Fitness

The seasonal outdoor pool operates from 10:00 AM to 10:00 PM. The fitness center includes ellipticals, treadmills, stationary bikes, free weights, resistance bands, and water station. All cardio equipment has flat screens and headphones.

Medical Center Location

Located 9 km from Ensemble/HCC and 25 km from William P. Hobby Airport. The hotel provides free shuttle service to Texas Medical Center. NRG Stadium and Arena are 1 mile away, making it convenient for Texans football games, concerts, and the Houston Livestock Show and Rodeo.

Business & Meeting Facilities

A 24-hour business center offers printing, copying, and scanning services. Meeting spaces include a dividable room accommodating up to 66 people and a conference room for 33 people. Equipment includes LCD projectors, flip charts, and teleconferencing capabilities.

“The Holiday Inn Express & Suites near the Medical Center struck me as particularly well-suited for longer stays, with its in-room workspaces and included breakfast; plus, the location balances proximity to medical facilities with access to Houston's cultural side. I appreciate that it's set up to handle both families and business travelers, without feeling sterile. This hotel seems to have a solid grasp on practical comforts.”
Hotel logo
Grace WhitmanContent & Editorial Director at Familyhotels
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Choose from a variety of room types

Choose from a wide variety of rooms designed for families, including double rooms, family suites, and rooms with breakfast included
Specialty Room
2 persons
Air conditioning
Suite Mobility Access Roll Shower or Non-Smoking
2 persons
1 King-size bed
Shower
Air conditioning
Suite Only Hearing Accessible
2 persons
2 King Size Beds
Air conditioning
King Suite Communication Accessible
2 persons
1 King-size bed and 1 Sofa bed
Air conditioning
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Availability and pricing for your selected dates

Book your family’s getaway in a snap with up-to-date availability and pricing!

Facilities

Each family-friendly hotel provides top-notch amenities for an unforgettable stay with your loved ones
Facilities: Perfect
9.1/10Review score

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Outdoor swimming pool

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg Location

9300 S Main Street, Houston, Texas, United States
Map view
9300 S Main Street, Houston, Texas, United States
Nearby
1000 Block South Loop
World Birding Center
1900 ft
Restaurants
Hank's Ice Cream Parlor
100 ft
9291 Main St
Popeyes Louisiana Kitchen
1.1 mi
9120 Main St
Sleepys Po-Boys
1.0 mi
9591 Main St
Five Guys
4900 ft
8505 S. Main Street Unit 380
Panda Express
4900 ft
8505 Main St
Denny's
1.5 mi
3332 S Loop W
Sonic Drive-In
1.1 mi
8504 Main Street
Explore Houston
Experience Houston
Top Attractions
Activities
Dining
Entertainment
NRG Stadium
17 minutes' walk
Home of the Houston Texans; a must-see for sports fans with tours available on non-game days.
Houston Zoo
50 minutes' walk
A premier zoological park hosting over 6,000 animals; great for families. Check for discount days.
Children's Museum of Houston
60 minutes' walk
Interactive exhibits designed for kids, encouraging creativity and learning; perfect for families.
Holocaust Museum Houston
35 minutes' walk
A moving tribute to Holocaust victims and survivors, showcasing educational exhibits and memorials.
Hermann Park
25 minutes' walk
A sprawling green space ideal for picnics, jogging, or relaxing under the trees; perfect for unwinding.
World Birding Center
10 minutes' walk
Nature reserve featuring birdwatching trails. A tranquil spot for wildlife enthusiasts and photographers.
Hank's Ice Cream Parlor
1 minute' walk
A local favorite known for its homemade ice cream. Perfect for a sweet treat after a long day.
Popeyes Louisiana Kitchen
25 minutes' walk
Famous for its spicy chicken and biscuits, offering a casual dining experience with quick service.
Sleepys Po-Boys
20 minutes' walk
New Orleans-style po-boys served in a cozy setting, boasting delicious sandwiches and local flavors.
Jazz Education
10 minutes' walk
A vibrant venue for live jazz music, hosting events that celebrate local talent and culture.
Six Flags Astroworld
20 minutes' drive
Amusement park featuring thrilling rides and family-friendly attractions. Great for adventure seekers.
Tips on navigating the city
City Centre
Houston15 min  ·  6.0 mi
Airports
William P. Hobby Airport (HOU)33 min  ·  13.7 mi
George Bush Intercontinental Airport - Houston (IAH)64 min  ·  26.2 mi
Train
Reliant Park Station23 min  ·  1.2 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
The hotel Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg serves a full breakfast for free. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of floors:
4
Number of rooms:
47
Former name
holiday inn express & suites houston s - medical ctr area, an ihg hotel

Family-focused reviews and ratings

Read feedback from other families who have stayed to ensure you make the right choice.
Review score
Based on 446 verified reviews
9.0/10
Perfect
91%
Recommend
Breakfast
7.6/10
Cleanliness
9.3/10
Comfort
9.3/10
Facilities
9.1/10
Free Wi-Fi
8.7/10
Location
9.0/10
Paid Wi-Fi
9.4/10
Staff
9.2/10
Value for money
8.6/10
Pros
Clean rooms
Good breakfast
Friendly staff
Cons
Soft bed
Broken windows
Guest reviews
based on 554 reviews
8.9/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
FAQs
About Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg
What time is check-in and check-out at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Check-in is from 15:00 and check-out is by 12:00.
How far is Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg from William P. Hobby Airport?
The hotel is 15 km from William P. Hobby Airport.
What amenities are available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel features free Wi-Fi, an outdoor swimming pool, a fitness center, and a business center.
Is parking available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Complimentary self-parking is available for guests on-site.
What nearby attractions can guests visit from Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Nearby attractions include NRG Stadium (1 km) and the Museum District (6 km).
What dining options are available at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel serves a complimentary hot breakfast daily; nearby dining options include Mama's Oven (0.5 km) and Pappas Bar-B-Q (1 km).
What room amenities can guests expect at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Rooms include a flat-screen TV, a coffee maker, a microwave, a refrigerator, and free toiletries.
Is there a fitness center at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
Yes, there is a fitness center available for guests.
What safety measures are in place at Holiday Inn Express & Suites Houston S - Medical Ctr Area By Ihg?
The hotel has safety measures including a security presence to ensure guest safety.

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